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                <OTQuestion id="d766ebbd-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page1.cml">
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                    <OTText id="d767af0e-60e4-11de-a0a3-ad581881fc2b" text="A protein that can puncture a cell wall:" />
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                <OTQuestion id="d76a4723-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page1.cml">
                  <prompt>
                    <OTText id="d76a4724-60e4-11de-a0a3-ad581881fc2b" text="A protein that forms a cable:" />
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                        <OTText id="d76a6e36-60e4-11de-a0a3-ad581881fc2b" text="protein 1" />
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                <OTQuestion id="d76abc59-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page1.cml">
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                    <OTText id="d76abc5a-60e4-11de-a0a3-ad581881fc2b" text="A protein that becomes a pore in a membrane:" />
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                    <OTChoice id="d76abc5b-60e4-11de-a0a3-ad581881fc2b" selectionUI="0">
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                        <OTText id="d76abc5c-60e4-11de-a0a3-ad581881fc2b" text="protein 1" />
                        <OTText id="d76abc5d-60e4-11de-a0a3-ad581881fc2b" text="protein 2" />
                        <OTText id="d76abc5e-60e4-11de-a0a3-ad581881fc2b" text="protein 3" />
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                <OTQuestion id="d92a6dbf-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page2.cml">
                  <prompt>
                    <OTText id="d92a6dc0-60e4-11de-a0a3-ad581881fc2b" text="Put a snapshot of the surface of the protein here." />
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                    <OTImage id="d92a6dc1-60e4-11de-a0a3-ad581881fc2b" />
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                <OTQuestion id="d92b5822-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page2.cml">
                  <prompt>
                    <OTText id="d92b5823-60e4-11de-a0a3-ad581881fc2b" text="Create an image that clearly shows both ends of the string of amino acids. In the snapshot, use the text annotation tool  to mark both ends." />
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                  <input>
                    <OTImage id="d92b5824-60e4-11de-a0a3-ad581881fc2b" />
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                <OTQuestion id="da787195-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page3.cml">
                  <prompt>
                    <OTText id="da787196-60e4-11de-a0a3-ad581881fc2b" text="" />
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                    <OTImage id="da787197-60e4-11de-a0a3-ad581881fc2b" />
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                <OTQuestion id="da787198-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page3.cml">
                  <prompt>
                    <OTText id="da7898a9-60e4-11de-a0a3-ad581881fc2b" text="Use the link above to open and explore the 20 rotatable 3D amino acids. Then select the &quot;Sidechain&quot; color scheme. The atoms that are colored gray are the same in every amino acid. What are they called?" />
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                  <input>
                    <OTChoice id="da7898aa-60e4-11de-a0a3-ad581881fc2b" selectionUI="0">
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                        <OTText id="da7898ab-60e4-11de-a0a3-ad581881fc2b" text="the sidechain atoms" />
                        <OTText id="da7898ac-60e4-11de-a0a3-ad581881fc2b" text="the backbone atoms" />
                        <OTText id="da7898ad-60e4-11de-a0a3-ad581881fc2b" text="the protein atoms" />
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                    <object refid="da7898ac-60e4-11de-a0a3-ad581881fc2b" />
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                <OTQuestion id="da78e6ce-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page3.cml">
                  <prompt>
                    <OTText id="da790ddf-60e4-11de-a0a3-ad581881fc2b" text="On the page of 3D amino acids, find glutamine and histidine. Use the different color schemes to select the true statement(s) below. (More than one statement may be true)." />
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                  <input>
                    <OTChoice id="da790de0-60e4-11de-a0a3-ad581881fc2b" selectionUI="1">
                      <choices>
                        <OTText id="da790de1-60e4-11de-a0a3-ad581881fc2b" text="they are both polar amino acids" />
                        <OTText id="da790de2-60e4-11de-a0a3-ad581881fc2b" text="one is polar and the other is non-polar" />
                        <OTText id="da790de3-60e4-11de-a0a3-ad581881fc2b" text="one of them is charged" />
                        <OTText id="da790de4-60e4-11de-a0a3-ad581881fc2b" text="they are both non-polar" />
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                <OTQuestion id="dba5f526-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page4.cml">
                  <prompt>
                    <OTText id="dba5f527-60e4-11de-a0a3-ad581881fc2b" text="Describe the distribution of electrons and polarity of an O-H bond." />
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                    <OTText id="dba61c38-60e4-11de-a0a3-ad581881fc2b" text="" />
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                <OTQuestion id="dba61c3a-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page4.cml">
                  <prompt>
                    <OTText id="dba61c3b-60e4-11de-a0a3-ad581881fc2b" text="Describe the distribution of electrons and polarity of a C-H bond." />
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                    <OTText id="dba61c3c-60e4-11de-a0a3-ad581881fc2b" text="" />
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                <OTQuestion id="ddb1cabe-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page5.cml">
                  <prompt>
                    <OTText id="ddb1cabf-60e4-11de-a0a3-ad581881fc2b" text="Snapshot of asparagine:" />
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                <OTQuestion id="ddca0db1-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page5.cml">
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                    <OTText id="ddca0db2-60e4-11de-a0a3-ad581881fc2b" text="Snapshot of leucine:" />
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                    <OTImage id="ddca0db3-60e4-11de-a0a3-ad581881fc2b" />
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                <OTQuestion id="ddca34c4-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page5.cml">
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                    <OTText id="ddca34c5-60e4-11de-a0a3-ad581881fc2b" text="Snapshot of threonine:" />
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                <OTQuestion id="ddca82e7-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page5.cml">
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                    <OTText id="ddca82e8-60e4-11de-a0a3-ad581881fc2b" text="For Asparagine, which surface shows the correct charges?" />
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                        <OTText id="ddca82ea-60e4-11de-a0a3-ad581881fc2b" text="surface 1" />
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                <OTQuestion id="ddcaa9fc-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page5.cml">
                  <prompt>
                    <OTText id="ddcaa9fd-60e4-11de-a0a3-ad581881fc2b" text="Which surface shows the correct charges for Leucine?" />
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                    <OTChoice id="ddcaa9fe-60e4-11de-a0a3-ad581881fc2b" selectionUI="0">
                      <choices>
                        <OTText id="ddcaa9ff-60e4-11de-a0a3-ad581881fc2b" text="surface 3" />
                        <OTText id="ddcaaa00-60e4-11de-a0a3-ad581881fc2b" text="surface 4" />
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                    <object refid="ddcaaa00-60e4-11de-a0a3-ad581881fc2b" />
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                <OTQuestion id="ddcad111-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page5.cml">
                  <prompt>
                    <OTText id="ddcad112-60e4-11de-a0a3-ad581881fc2b" text="Which surface shows the correct charges for Threonine?" />
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                  <input>
                    <OTChoice id="ddcad113-60e4-11de-a0a3-ad581881fc2b" selectionUI="0">
                      <choices>
                        <OTText id="ddcad114-60e4-11de-a0a3-ad581881fc2b" text="surface 5" />
                        <OTText id="ddcad115-60e4-11de-a0a3-ad581881fc2b" text="surface 6" />
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                    <object refid="ddcad114-60e4-11de-a0a3-ad581881fc2b" />
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                <OTQuestion id="ddcaf826-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page5.cml">
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                    <OTText id="ddcaf827-60e4-11de-a0a3-ad581881fc2b">
                      <text>Choose the best way to complete this sentence:
When two atoms in a bond have very different electronegativities, the surface of the molecule...</text>
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                    <OTChoice id="ddcaf828-60e4-11de-a0a3-ad581881fc2b" selectionUI="0">
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                        <OTText id="ddcaf829-60e4-11de-a0a3-ad581881fc2b" text="has no charge." />
                        <OTText id="ddcaf82a-60e4-11de-a0a3-ad581881fc2b" text="has regions of positive and negative charge." />
                        <OTText id="ddcb1f3b-60e4-11de-a0a3-ad581881fc2b" text="has a negative charge." />
                        <OTText id="ddcb1f3c-60e4-11de-a0a3-ad581881fc2b" text="has a positive charge." />
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                    <object refid="ddcaf82a-60e4-11de-a0a3-ad581881fc2b" />
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                <OTQuestion id="ddcb1f3d-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page5.cml">
                  <prompt>
                    <OTText id="ddcb1f3e-60e4-11de-a0a3-ad581881fc2b" text="Explain how the colors on the surfaces of the side chains indicate whether it is polar or non-polar." />
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                    <OTText id="ddcb1f3f-60e4-11de-a0a3-ad581881fc2b" text="" />
                  </input>
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                <OTQuestion id="df6a2941-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page6.cml">
                  <prompt>
                    <OTText id="df6a5052-60e4-11de-a0a3-ad581881fc2b" text="Is water a polar or non-polar molecule? Explain your answer by writing about the bonds in water." />
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                  <input>
                    <OTText id="df6a5053-60e4-11de-a0a3-ad581881fc2b" text="" />
                  </input>
                </OTQuestion>
                <OTQuestion id="df6a7765-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page6.cml">
                  <prompt>
                    <OTText id="df6a7766-60e4-11de-a0a3-ad581881fc2b" text="Which type of amino acid is hydrophobic?" />
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                  <input>
                    <OTChoice id="df6a7767-60e4-11de-a0a3-ad581881fc2b" selectionUI="0">
                      <choices>
                        <OTText id="df6a7768-60e4-11de-a0a3-ad581881fc2b" text="polar" />
                        <OTText id="df6a7769-60e4-11de-a0a3-ad581881fc2b" text="non-polar" />
                        <OTText id="df6a9e7a-60e4-11de-a0a3-ad581881fc2b" text="neither - they both don't attract water very well" />
                        <OTText id="df6a9e7b-60e4-11de-a0a3-ad581881fc2b" text="neither - they attract the water molecules equally" />
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                    <object refid="df6a7769-60e4-11de-a0a3-ad581881fc2b" />
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                <OTQuestion id="df6ac58c-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page6.cml">
                  <prompt>
                    <OTText id="df6ac58d-60e4-11de-a0a3-ad581881fc2b" text="Use your knowledge of positive and negative charge to explain why polar molecules attract each other and water better than non-polar molecules." />
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                  <input>
                    <OTText id="df6ac58e-60e4-11de-a0a3-ad581881fc2b" text="" />
                  </input>
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                <OTQuestion id="df6aeca0-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page6.cml">
                  <prompt>
                    <OTText id="df6aeca1-60e4-11de-a0a3-ad581881fc2b" text="Which solvent(s) leads to folding of the protein?" />
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                  <input>
                    <OTChoice id="df6aeca2-60e4-11de-a0a3-ad581881fc2b" selectionUI="0">
                      <choices>
                        <OTText id="df6aeca3-60e4-11de-a0a3-ad581881fc2b" text="both water and oil" />
                        <OTText id="df6aeca4-60e4-11de-a0a3-ad581881fc2b" text="neither water nor oil" />
                        <OTText id="df6aeca5-60e4-11de-a0a3-ad581881fc2b" text="water" />
                        <OTText id="df6aeca6-60e4-11de-a0a3-ad581881fc2b" text="oil" />
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                  <correctAnswer>
                    <object refid="df6aeca5-60e4-11de-a0a3-ad581881fc2b" />
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                <OTQuestion id="df6b3ac7-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page6.cml">
                  <prompt>
                    <OTText id="df6b3ac8-60e4-11de-a0a3-ad581881fc2b" text="Where do the amino acids with polar side chains end up when the protein chain folds?" />
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                  <input>
                    <OTChoice id="df6b3ac9-60e4-11de-a0a3-ad581881fc2b" selectionUI="0">
                      <choices>
                        <OTText id="df6b61da-60e4-11de-a0a3-ad581881fc2b" text="evenly throughout the folded protein" />
                        <OTText id="df6b61db-60e4-11de-a0a3-ad581881fc2b" text="mostly inside the folded protein" />
                        <OTText id="df6b61dc-60e4-11de-a0a3-ad581881fc2b" text="mostly on the outside of the folded protein" />
                      </choices>
                    </OTChoice>
                  </input>
                  <correctAnswer>
                    <object refid="df6b61dc-60e4-11de-a0a3-ad581881fc2b" />
                  </correctAnswer>
                </OTQuestion>
                <OTQuestion id="e29f3cad-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page8.cml">
                  <prompt>
                    <OTText id="e29f3cae-60e4-11de-a0a3-ad581881fc2b" text="Snapshot of an alpha helix:" />
                  </prompt>
                  <input>
                    <OTImage id="e29f3caf-60e4-11de-a0a3-ad581881fc2b" />
                  </input>
                </OTQuestion>
                <OTQuestion id="e29f8ad0-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page8.cml">
                  <prompt>
                    <OTText id="e29f8ad1-60e4-11de-a0a3-ad581881fc2b" text="Snapshot of a beta sheet:" />
                  </prompt>
                  <input>
                    <OTImage id="e29f8ad2-60e4-11de-a0a3-ad581881fc2b" />
                  </input>
                </OTQuestion>
                <OTQuestion id="e29fb1e3-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page8.cml">
                  <prompt>
                    <OTText id="e29fb1e4-60e4-11de-a0a3-ad581881fc2b" text="A loop between a beta sheet and an alpha helix:" />
                  </prompt>
                  <input>
                    <OTImage id="e29fb1e5-60e4-11de-a0a3-ad581881fc2b" />
                  </input>
                </OTQuestion>
                <OTQuestion id="e4061fb6-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page9.cml">
                  <prompt>
                    <OTText id="e4061fb7-60e4-11de-a0a3-ad581881fc2b" text="The hydrogen bonds that stabilize an alpha helix." />
                  </prompt>
                  <input>
                    <OTImage id="e4061fb8-60e4-11de-a0a3-ad581881fc2b" />
                  </input>
                </OTQuestion>
                <OTQuestion id="e40646c9-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page9.cml">
                  <prompt>
                    <OTText id="e40646ca-60e4-11de-a0a3-ad581881fc2b" text="The hydrogen bonds that stabilize a beta sheet." />
                  </prompt>
                  <input>
                    <OTImage id="e40646cb-60e4-11de-a0a3-ad581881fc2b" />
                  </input>
                </OTQuestion>
                <OTQuestion id="e4066ddc-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page9.cml">
                  <prompt>
                    <OTText id="e4066ddd-60e4-11de-a0a3-ad581881fc2b" text="Hydrogen bonds stabilizing alpha helices and beta sheets form between the atoms of which part(s) of the amino acids involved?" />
                  </prompt>
                  <input>
                    <OTChoice id="e4066dde-60e4-11de-a0a3-ad581881fc2b" selectionUI="0">
                      <choices>
                        <OTText id="e422333f-60e4-11de-a0a3-ad581881fc2b" text="the side chains" />
                        <OTText id="e4225a50-60e4-11de-a0a3-ad581881fc2b" text="the side chains and backbone" />
                        <OTText id="e4225a51-60e4-11de-a0a3-ad581881fc2b" text="the backbone" />
                      </choices>
                    </OTChoice>
                  </input>
                  <correctAnswer>
                    <object refid="e4225a51-60e4-11de-a0a3-ad581881fc2b" />
                  </correctAnswer>
                </OTQuestion>
                <OTQuestion id="e4228162-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page9.cml">
                  <prompt>
                    <OTText id="e4228163-60e4-11de-a0a3-ad581881fc2b" text="Place a snapshot here that illustrates your answer to the previous question." />
                  </prompt>
                  <input>
                    <OTImage id="e4228164-60e4-11de-a0a3-ad581881fc2b" />
                  </input>
                </OTQuestion>
                <OTQuestion id="e5ac0795-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page10.cml">
                  <prompt>
                    <OTText id="e5ac0796-60e4-11de-a0a3-ad581881fc2b" text="Show an interaction that stabilizes an alpha helix and a loop:" />
                  </prompt>
                  <input>
                    <OTImage id="e5ac0797-60e4-11de-a0a3-ad581881fc2b" />
                  </input>
                </OTQuestion>
                <OTQuestion id="e5ac2ea8-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page10.cml">
                  <prompt>
                    <OTText id="e5ac2ea9-60e4-11de-a0a3-ad581881fc2b" text="Show an interaction that stabilizes two alpha helices:" />
                  </prompt>
                  <input>
                    <OTImage id="e5ac2eaa-60e4-11de-a0a3-ad581881fc2b" />
                  </input>
                </OTQuestion>
                <OTQuestion id="e5ac55bb-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page10.cml">
                  <prompt>
                    <OTText id="e5ac55bc-60e4-11de-a0a3-ad581881fc2b" text="Show an interaction that stabilizes a loop and a beta sheet:" />
                  </prompt>
                  <input>
                    <OTImage id="e5ac55bd-60e4-11de-a0a3-ad581881fc2b" />
                  </input>
                </OTQuestion>
                <OTQuestion id="e5ac55be-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page10.cml">
                  <prompt>
                    <OTText id="e5ac7ccf-60e4-11de-a0a3-ad581881fc2b" text="Show the hydrophobic core:" />
                  </prompt>
                  <input>
                    <OTImage id="e5ac7cd0-60e4-11de-a0a3-ad581881fc2b" />
                  </input>
                </OTQuestion>
                <OTQuestion id="e75c0191-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page11.cml">
                  <prompt>
                    <OTText id="e75c0192-60e4-11de-a0a3-ad581881fc2b" text="On the left is a different small molecule than NAD. Why wouldn't this molecule bind to alcohol dehydrogenase in place of NAD? (Choose the BEST answer below)." />
                  </prompt>
                  <input>
                    <OTChoice id="e75c0193-60e4-11de-a0a3-ad581881fc2b" selectionUI="0">
                      <choices>
                        <OTText id="e75c0194-60e4-11de-a0a3-ad581881fc2b" text="it is not the same as NAD" />
                        <OTText id="e75c0195-60e4-11de-a0a3-ad581881fc2b" text="it is smaller than NAD" />
                        <OTText id="e75c0196-60e4-11de-a0a3-ad581881fc2b" text="it is too large to fit in the NAD site" />
                        <OTText id="e75c28a7-60e4-11de-a0a3-ad581881fc2b" text="it's the wrong shape, and will not form attractions with the site" />
                      </choices>
                    </OTChoice>
                  </input>
                  <correctAnswer>
                    <object refid="e75c0194-60e4-11de-a0a3-ad581881fc2b" />
                  </correctAnswer>
                </OTQuestion>
                <OTQuestion id="e75c4fb8-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page11.cml">
                  <prompt>
                    <OTText id="e75c4fb9-60e4-11de-a0a3-ad581881fc2b" text="What would you expect to happen to the function of proteins at very high temperatures?" />
                  </prompt>
                  <input>
                    <OTChoice id="e75c4fba-60e4-11de-a0a3-ad581881fc2b" selectionUI="0">
                      <choices>
                        <OTText id="e75c4fbb-60e4-11de-a0a3-ad581881fc2b" text="the functions would not be affected" />
                        <OTText id="e75c4fbc-60e4-11de-a0a3-ad581881fc2b" text="the proteins would not be able to function anymore" />
                        <OTText id="e75c4fbd-60e4-11de-a0a3-ad581881fc2b" text="the functions would happen faster" />
                      </choices>
                    </OTChoice>
                  </input>
                  <correctAnswer>
                    <object refid="e75c4fbb-60e4-11de-a0a3-ad581881fc2b" />
                  </correctAnswer>
                </OTQuestion>
                <OTQuestion id="e75c76ce-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page11.cml">
                  <prompt>
                    <OTText id="e75c76cf-60e4-11de-a0a3-ad581881fc2b" text="Explain how protein folding fits in to your answer to the previous question." />
                  </prompt>
                  <input>
                    <OTText id="e75c76d0-60e4-11de-a0a3-ad581881fc2b" text="" />
                  </input>
                </OTQuestion>
                <OTQuestion id="ec24fb62-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page12.cml">
                  <prompt>
                    <OTText id="ec252273-60e4-11de-a0a3-ad581881fc2b" text="Does TNF have the quaternary level of structure? Make sure to try different color schemes on the model of TNF above." />
                  </prompt>
                  <input>
                    <OTChoice id="ec252274-60e4-11de-a0a3-ad581881fc2b" selectionUI="0">
                      <choices>
                        <OTText id="ec252275-60e4-11de-a0a3-ad581881fc2b" text="yes" />
                        <OTText id="ec252276-60e4-11de-a0a3-ad581881fc2b" text="no" />
                        <OTText id="ec252277-60e4-11de-a0a3-ad581881fc2b" text="it's impossible to tell." />
                      </choices>
                    </OTChoice>
                  </input>
                  <correctAnswer>
                    <object refid="ec252275-60e4-11de-a0a3-ad581881fc2b" />
                  </correctAnswer>
                </OTQuestion>
                <OTQuestion id="ec254988-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page12.cml">
                  <prompt>
                    <OTText id="ec254989-60e4-11de-a0a3-ad581881fc2b" text="Explain your answer to the previous question:" />
                  </prompt>
                  <input>
                    <OTText id="ec25498a-60e4-11de-a0a3-ad581881fc2b" text="" />
                  </input>
                </OTQuestion>
                <OTQuestion id="ef9961ac-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page13.cml">
                  <prompt>
                    <OTText id="ef9988bd-60e4-11de-a0a3-ad581881fc2b" text="The &quot;primary structure&quot; of a protein refers to:" />
                  </prompt>
                  <input>
                    <OTChoice id="ef9988be-60e4-11de-a0a3-ad581881fc2b" selectionUI="0">
                      <choices>
                        <OTText id="ef9988bf-60e4-11de-a0a3-ad581881fc2b" text="the folds of the protein" />
                        <OTText id="ef9988c0-60e4-11de-a0a3-ad581881fc2b" text="the alpha helix and beta sheet structures" />
                        <OTText id="ef9988c1-60e4-11de-a0a3-ad581881fc2b" text="the sequence of amino acids in the protein" />
                        <OTText id="ef9988c2-60e4-11de-a0a3-ad581881fc2b" text="two proteins that function as a unit" />
                      </choices>
                    </OTChoice>
                  </input>
                  <correctAnswer>
                    <object refid="ef9988c1-60e4-11de-a0a3-ad581881fc2b" />
                  </correctAnswer>
                </OTQuestion>
                <OTQuestion id="ef9a4c13-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page13.cml">
                  <prompt>
                    <OTText id="ef9a7324-60e4-11de-a0a3-ad581881fc2b" text="What part of an amino acid has properties (shape, charge) that are different from other amino acids?" />
                  </prompt>
                  <input>
                    <OTChoice id="ef9a7325-60e4-11de-a0a3-ad581881fc2b" selectionUI="0">
                      <choices>
                        <OTText id="ef9a7326-60e4-11de-a0a3-ad581881fc2b" text="the side chain" />
                        <OTText id="ef9a7327-60e4-11de-a0a3-ad581881fc2b" text="the backbone atoms" />
                        <OTText id="ef9a7328-60e4-11de-a0a3-ad581881fc2b" text="the secondary structure" />
                        <OTText id="ef9a7329-60e4-11de-a0a3-ad581881fc2b" text="none of the above" />
                      </choices>
                    </OTChoice>
                  </input>
                  <correctAnswer>
                    <object refid="ef9a7326-60e4-11de-a0a3-ad581881fc2b" />
                  </correctAnswer>
                </OTQuestion>
                <OTQuestion id="ef9a9a3a-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page13.cml">
                  <prompt>
                    <OTText id="ef9a9a3b-60e4-11de-a0a3-ad581881fc2b" text="The bond between two atoms of equal electronegativity is:" />
                  </prompt>
                  <input>
                    <OTChoice id="ef9a9a3c-60e4-11de-a0a3-ad581881fc2b" selectionUI="0">
                      <choices>
                        <OTText id="ef9a9a3d-60e4-11de-a0a3-ad581881fc2b" text="polar" />
                        <OTText id="ef9a9a3e-60e4-11de-a0a3-ad581881fc2b" text="hydrophilic" />
                        <OTText id="ef9a9a3f-60e4-11de-a0a3-ad581881fc2b" text="nonpolar" />
                      </choices>
                    </OTChoice>
                  </input>
                  <correctAnswer>
                    <object refid="ef9a9a3f-60e4-11de-a0a3-ad581881fc2b" />
                  </correctAnswer>
                </OTQuestion>
                <OTQuestion id="ef9ac150-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page13.cml">
                  <prompt>
                    <OTText id="ef9ac151-60e4-11de-a0a3-ad581881fc2b" text="The protein shown at right has folded in water. Which of the following statements about it is FALSE?" />
                  </prompt>
                  <input>
                    <OTChoice id="ef9ac152-60e4-11de-a0a3-ad581881fc2b" selectionUI="0">
                      <choices>
                        <OTText id="ef9ac153-60e4-11de-a0a3-ad581881fc2b" text="amino acid 14 is most likely hydrophobic" />
                        <OTText id="ef9ac154-60e4-11de-a0a3-ad581881fc2b" text="amino acid 17 is most likely polar" />
                        <OTText id="ef9ac155-60e4-11de-a0a3-ad581881fc2b" text="amino acid 22 is most likely polar" />
                        <OTText id="ef9ac156-60e4-11de-a0a3-ad581881fc2b" text="amino acid 20 is most likely hydrophilic" />
                      </choices>
                    </OTChoice>
                  </input>
                  <correctAnswer>
                    <object refid="ef9ac155-60e4-11de-a0a3-ad581881fc2b" />
                  </correctAnswer>
                </OTQuestion>
                <OTQuestion id="ef9ae867-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page13.cml">
                  <prompt>
                    <OTText id="ef9ae868-60e4-11de-a0a3-ad581881fc2b" text="Which of the following do hydrogen bonds help to stabilize?" />
                  </prompt>
                  <input>
                    <OTChoice id="ef9ae869-60e4-11de-a0a3-ad581881fc2b" selectionUI="0">
                      <choices>
                        <OTText id="ef9ae86a-60e4-11de-a0a3-ad581881fc2b" text="primary structure" />
                        <OTText id="ef9ae86b-60e4-11de-a0a3-ad581881fc2b" text="secondary structure" />
                        <OTText id="ef9ae86c-60e4-11de-a0a3-ad581881fc2b" text="tertiary structure" />
                        <OTText id="ef9ae86d-60e4-11de-a0a3-ad581881fc2b" text="quaternary structure" />
                        <OTText id="ef9ae86e-60e4-11de-a0a3-ad581881fc2b" text="B, C, and D are correct" />
                      </choices>
                    </OTChoice>
                  </input>
                  <correctAnswer>
                    <object refid="ef9ae86e-60e4-11de-a0a3-ad581881fc2b" />
                  </correctAnswer>
                </OTQuestion>
                <OTQuestion id="ef9b0f7f-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page13.cml">
                  <prompt>
                    <OTText id="ef9b0f80-60e4-11de-a0a3-ad581881fc2b">
                      <text>Select two correct choices:
A protein with quaternary structure...</text>
                    </OTText>
                  </prompt>
                  <input>
                    <OTChoice id="ef9b0f81-60e4-11de-a0a3-ad581881fc2b" selectionUI="1">
                      <choices>
                        <OTText id="ef9b0f82-60e4-11de-a0a3-ad581881fc2b" text="is made of two or more strings of amino acids" />
                        <OTText id="ef9b0f83-60e4-11de-a0a3-ad581881fc2b" text="is always composed of identical subunits" />
                        <OTText id="ef9b3694-60e4-11de-a0a3-ad581881fc2b" text="is always composed of different subunits" />
                        <OTText id="ef9b3695-60e4-11de-a0a3-ad581881fc2b" text="can be a mix of identical and different subunits" />
                      </choices>
                    </OTChoice>
                  </input>
                  <correctAnswer>
                    <OTObjectSet>
                      <objects>
                        <object refid="ef9b0f82-60e4-11de-a0a3-ad581881fc2b" />
                        <object refid="ef9b3695-60e4-11de-a0a3-ad581881fc2b" />
                      </objects>
                    </OTObjectSet>
                  </correctAnswer>
                </OTQuestion>
                <OTQuestion id="ef9b5da7-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page13.cml">
                  <prompt>
                    <OTText id="ef9b5da8-60e4-11de-a0a3-ad581881fc2b" text="Two amino acids that are far apart from each other in the primary structure of a protein can be touching each other in the tertiary structure of the same protein. Explain how this happens." />
                  </prompt>
                  <input>
                    <OTText id="ef9b5da9-60e4-11de-a0a3-ad581881fc2b" text="" />
                  </input>
                </OTQuestion>
                <OTQuestion id="ef9b5dab-60e4-11de-a0a3-ad581881fc2b" name="http://ri-itest.concord.org/SAMActivities/FourLevelsOfProteinStruct/FourLevelsOfProteinStruct_v3/page13.cml">
                  <prompt>
                    <OTText id="ef9b5dac-60e4-11de-a0a3-ad581881fc2b" text="Why do defects in protein folding cause disease?" />
                  </prompt>
                  <input>
                    <OTText id="ef9b5dad-60e4-11de-a0a3-ad581881fc2b" text="" />
                  </input>
                </OTQuestion>
              </questions>
            </OTModelerPage>
            <OTWorkgroupMemberChooser />
          </layers>
        </OTLayerContainer>
      </root>
    </OTSystem>
  </objects>
</otrunk>

