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                <OTQuestion id="ffc9de22-600b-11de-8d0a-0ff0a568be04" name="http://ri-itest.concord.org/SAMActivities/DNAToProteins/DNAToProteins_v3/page2.cml">
                  <prompt>
                    <OTText id="ffcac883-600b-11de-8d0a-0ff0a568be04" text="Take a snapshot that best shows that DNA is really two separate molecules wrapping around each other. And then follow the instruction below to drag the image in." />
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                    <OTText id="ffcdfcd6-600b-11de-8d0a-0ff0a568be04" text="Take a snapshot that best illustrates the hydrogen bonds which attract the two strands together. And then follow the instruction below to drag an image in." />
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                  <prompt>
                    <OTText id="02babc89-600c-11de-8d0a-0ff0a568be04" text="In this model, the bottom DNA strand is transcribed. Which DNA strand is most similar to the RNA strand?" />
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                        <OTText id="02bb58cb-600c-11de-8d0a-0ff0a568be04" text="The top DNA strand." />
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                <OTQuestion id="02bb58cd-600c-11de-8d0a-0ff0a568be04" name="http://ri-itest.concord.org/SAMActivities/DNAToProteins/DNAToProteins_v3/page4.cml">
                  <prompt>
                    <OTText id="02bb58ce-600c-11de-8d0a-0ff0a568be04" text="A group of three nucleotides codes for one amino acid. Notice the black tick marks above the DNA strand showing these triplet groups. How many amino acids are coded for by the strand in the model above?" />
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                    <OTChoice id="02bb7fdf-600c-11de-8d0a-0ff0a568be04" selectionUI="0">
                      <choices>
                        <OTText id="02bb7fe0-600c-11de-8d0a-0ff0a568be04" text="3." />
                        <OTText id="02bb7fe1-600c-11de-8d0a-0ff0a568be04" text="12." />
                        <OTText id="02bba6f2-600c-11de-8d0a-0ff0a568be04" text="24." />
                        <OTText id="02bba6f3-600c-11de-8d0a-0ff0a568be04" text="30." />
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                    <object refid="02bb7fe1-600c-11de-8d0a-0ff0a568be04" />
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                <OTQuestion id="02bc6a44-600c-11de-8d0a-0ff0a568be04" name="http://ri-itest.concord.org/SAMActivities/DNAToProteins/DNAToProteins_v3/page4.cml">
                  <prompt>
                    <OTText id="02bc6a45-600c-11de-8d0a-0ff0a568be04" text="List two ways in which the RNA strand in the model above is different than the DNA strand from which it was copied (the template strand)." />
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                    <OTText id="02bc6a46-600c-11de-8d0a-0ff0a568be04" text="" />
                  </input>
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                <OTQuestion id="02bc9158-600c-11de-8d0a-0ff0a568be04" name="http://ri-itest.concord.org/SAMActivities/DNAToProteins/DNAToProteins_v3/page4.cml">
                  <prompt>
                    <OTText id="02bc9159-600c-11de-8d0a-0ff0a568be04" text="If six bases on the template strand of DNA are AGTAAC, what are the six bases on the complementary section of the RNA?" />
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                    <OTText id="02bc915a-600c-11de-8d0a-0ff0a568be04" text="" />
                  </input>
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                <OTQuestion id="0446178c-600c-11de-8d0a-0ff0a568be04" name="http://ri-itest.concord.org/SAMActivities/DNAToProteins/DNAToProteins_v3/page5.cml">
                  <prompt>
                    <OTText id="0446178d-600c-11de-8d0a-0ff0a568be04" text="Describe each step as the RNA is translated." />
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                  <input>
                    <OTText id="0446178e-600c-11de-8d0a-0ff0a568be04" text="" />
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                </OTQuestion>
                <OTQuestion id="04461790-600c-11de-8d0a-0ff0a568be04" name="http://ri-itest.concord.org/SAMActivities/DNAToProteins/DNAToProteins_v3/page5.cml">
                  <prompt>
                    <OTText id="04461791-600c-11de-8d0a-0ff0a568be04" text="Compare the sequence and shape of both proteins that are formed." />
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                    <OTText id="04461792-600c-11de-8d0a-0ff0a568be04" text="" />
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                <OTQuestion id="07de3274-600c-11de-8d0a-0ff0a568be04" name="http://ri-itest.concord.org/SAMActivities/DNAToProteins/DNAToProteins_v3/page7.cml">
                  <prompt>
                    <OTText id="07de5985-600c-11de-8d0a-0ff0a568be04" text="Drag a snapshot image that shows the synthesized protein before mutation." />
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                  <input>
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                </OTQuestion>
                <OTQuestion id="07de5987-600c-11de-8d0a-0ff0a568be04" name="http://ri-itest.concord.org/SAMActivities/DNAToProteins/DNAToProteins_v3/page7.cml">
                  <prompt>
                    <OTText id="07de5988-600c-11de-8d0a-0ff0a568be04" text="Drag a snapshot image that shows the synthesized protein after mutation." />
                  </prompt>
                  <input>
                    <OTImage id="07de5989-600c-11de-8d0a-0ff0a568be04" />
                  </input>
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                <OTQuestion id="07de809a-600c-11de-8d0a-0ff0a568be04" name="http://ri-itest.concord.org/SAMActivities/DNAToProteins/DNAToProteins_v3/page7.cml">
                  <prompt>
                    <OTText id="07de809b-600c-11de-8d0a-0ff0a568be04" text="Some substitution mutations result in a malfunctioning protein, but others do not. Why is this?" />
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                <OTQuestion id="0913f35e-600c-11de-8d0a-0ff0a568be04" name="http://ri-itest.concord.org/SAMActivities/DNAToProteins/DNAToProteins_v3/page8.cml">
                  <prompt>
                    <OTText id="0913f35f-600c-11de-8d0a-0ff0a568be04" text="How did you create a silent mutation? Explain, giving the code for the triplet where you made your substitution, before and after the mutation." />
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                    <OTText id="0913f360-600c-11de-8d0a-0ff0a568be04" text="" />
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                  <prompt>
                    <OTText id="0a6f8bc3-600c-11de-8d0a-0ff0a568be04" text="Drag a snapshot image that shows the mutated protein." />
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                    <OTImage id="0a6f8bc4-600c-11de-8d0a-0ff0a568be04" />
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                  <prompt>
                    <OTText id="0a6fb2d6-600c-11de-8d0a-0ff0a568be04" text="Why do mutations that create a stop codon have a bigger effect on the protein than other mutations?" />
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                  <prompt>
                    <OTText id="0c4b77ba-600c-11de-8d0a-0ff0a568be04" text="Drag a snapshot image that shows the original protein before mutation." />
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                    <OTImage id="0c4b77bb-600c-11de-8d0a-0ff0a568be04" />
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                  <prompt>
                    <OTText id="0c4b9ecd-600c-11de-8d0a-0ff0a568be04" text="Drag a snapshot image that shows the mutant protein." />
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                    <OTImage id="0c4b9ece-600c-11de-8d0a-0ff0a568be04" />
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                  <prompt>
                    <OTText id="0c4bc5e0-600c-11de-8d0a-0ff0a568be04" text="Why do insertion mutations have a bigger effect on the protein than substitution mutations?" />
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                    <OTText id="0c4bc5e1-600c-11de-8d0a-0ff0a568be04" text="" />
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                <OTQuestion id="0c4becf3-600c-11de-8d0a-0ff0a568be04" name="http://ri-itest.concord.org/SAMActivities/DNAToProteins/DNAToProteins_v3/page10.cml">
                  <prompt>
                    <OTText id="0c4becf4-600c-11de-8d0a-0ff0a568be04" text="How did you make an insertion or deletion mutation that did not cause a frame-shift?" />
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                <OTQuestion id="101b4477-600c-11de-8d0a-0ff0a568be04" name="http://ri-itest.concord.org/SAMActivities/DNAToProteins/DNAToProteins_v3/page11.cml">
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                    <OTText id="101b4478-600c-11de-8d0a-0ff0a568be04" text="The process by which the genetic code of DNA is copied into a strand of RNA is called" />
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                    <OTChoice id="101b4479-600c-11de-8d0a-0ff0a568be04" selectionUI="0">
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                        <OTText id="101b447a-600c-11de-8d0a-0ff0a568be04" text="translation." />
                        <OTText id="101b6b8b-600c-11de-8d0a-0ff0a568be04" text="transcription." />
                        <OTText id="101b6b8c-600c-11de-8d0a-0ff0a568be04" text="transformation." />
                        <OTText id="101b6b8d-600c-11de-8d0a-0ff0a568be04" text="replication." />
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                    <object refid="101b6b8b-600c-11de-8d0a-0ff0a568be04" />
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                <OTQuestion id="101b6b8e-600c-11de-8d0a-0ff0a568be04" name="http://ri-itest.concord.org/SAMActivities/DNAToProteins/DNAToProteins_v3/page11.cml">
                  <prompt>
                    <OTText id="101b6b8f-600c-11de-8d0a-0ff0a568be04" text="Which one of the following is the place where genetic information is stored in the cell?" />
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                    <OTChoice id="101b6b90-600c-11de-8d0a-0ff0a568be04" selectionUI="0">
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                        <OTText id="101b92a1-600c-11de-8d0a-0ff0a568be04" text="Strands of mRNA." />
                        <OTText id="101b92a2-600c-11de-8d0a-0ff0a568be04" text="Individual nucleotides." />
                        <OTText id="101b92a3-600c-11de-8d0a-0ff0a568be04" text="Strands of DNA." />
                        <OTText id="101b92a4-600c-11de-8d0a-0ff0a568be04" text="Individual amino acids." />
                        <OTText id="101b92a5-600c-11de-8d0a-0ff0a568be04" text="Proteins." />
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                <OTQuestion id="101be0c6-600c-11de-8d0a-0ff0a568be04" name="http://ri-itest.concord.org/SAMActivities/DNAToProteins/DNAToProteins_v3/page11.cml">
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                    <OTText id="101be0c7-600c-11de-8d0a-0ff0a568be04" text="How can a mutation have no effect?" />
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                    <OTText id="101be0c8-600c-11de-8d0a-0ff0a568be04" text="" />
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                <OTQuestion id="101c07da-600c-11de-8d0a-0ff0a568be04" name="http://ri-itest.concord.org/SAMActivities/DNAToProteins/DNAToProteins_v3/page11.cml">
                  <prompt>
                    <OTText id="101c07db-600c-11de-8d0a-0ff0a568be04" text="What is the connection between the DNA sequence of a gene and the amino acid sequence of the protein that is produced from that gene?" />
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                    <OTText id="101c07dc-600c-11de-8d0a-0ff0a568be04" text="" />
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                <OTQuestion id="101c2eee-600c-11de-8d0a-0ff0a568be04" name="http://ri-itest.concord.org/SAMActivities/DNAToProteins/DNAToProteins_v3/page11.cml">
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                    <OTText id="101c2eef-600c-11de-8d0a-0ff0a568be04">
                      <text>How many nucleotides would you need to code for a protein with the following amino acid sequence? (There are 24 amino acids.)

Ala-Ala-Met-Ile-Leu-Val-Phe-Tyr-Try-Trp-Pro-Ser- -Trp-His-Lys-Lys-Ala-Gly-Val-Arg-Asn-Cys-His-Gly</text>
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                        <OTText id="101c2ef1-600c-11de-8d0a-0ff0a568be04" text="8." />
                        <OTText id="101c2ef2-600c-11de-8d0a-0ff0a568be04" text="24." />
                        <OTText id="101c7d13-600c-11de-8d0a-0ff0a568be04" text="72." />
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                <OTQuestion id="101ca424-600c-11de-8d0a-0ff0a568be04" name="http://ri-itest.concord.org/SAMActivities/DNAToProteins/DNAToProteins_v3/page11.cml">
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                    <OTText id="101ca425-600c-11de-8d0a-0ff0a568be04" text="Which types of mutation, among those you created in this activity, are more likely to be lethal? Why?" />
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